A General Purpose Anti-Infective

Extending the Utility of Non-Pharmaceutical Interventions

 
 

ViruSAL - Upper Respiratory

Tract and Nasopharyngeal Hygiene

Exerting a Surface Adhesion Limiting Effect on Enveloped Viruses and Bacteria.

Including; Rhinovirus, Influenza, Para-Influenza, RSV, Coronavirus and others

 
 
 
 
 
 

ViruSAL is Effective against at least 88% of all Respiratory Viruses*

*Based on In Vitro efficacy against enveloped species

 
 
 
 
 

Potent and Rapid Efficacy against SARS-CoV-2

Physiologically Relevant Human Bronchial Epithelial Cells grown in air / liquid Interface culture

Pre-Infection:

ViruSAL treated 1 hour prior to infection No Viable Virus Recoverable

Post-Infection:

ViruSAL Treated 1 hour after infection. No Viable Virus Recoverable

 
 
 

ViruSAL is Safe and Non-Toxic: Contains no Active Pharmaceutical Ingredients

 
 

ViruSAL is a composition of Pharmacopoeia Monographed Excipients, Exerting Potent Anti-Infective Properties Without Harming Human Tissue. A Novel Technolgy, Patented Worldwide.

 
 
 
 

Cytotoxicity Study:

Human Bronchial Epithelium Cells grown under Air / Liquid Interface conditions

A: Cells treated with ViruSAL or buffer control at varying concentrations for 15 minutes.

B: Cells treated with 3% ViruSAL or buffer control for varying time periods. Triton X-100 positive control. MTT assay performed 72 hours after treatment

 
 

ViruSAL is non-toxic to human cells

ViruSAL Mammalian Cell Cytotoxicity is almost negligible compared to Chlorhexidine and other conventional agents that are commonly used as Anti-Infectives.Although not systemically active, all of the constituents of ViruSAL are compatible and safe with human systemic exposure.

 
 
 
 
 
 

Effective against Enveloped Viruses, Bacteria and Yeast

 
 

ViruSAL is Amphipathic and Modulates Hydrophilic / Lipophilic Balance at a Cell Surface. Anti-Infective Properties are due to Inhibition of Adhesion and Perturbation of Microbial Cell Membrane

 
 

Efficacy against Established Microbial Biofilm: ViruSAL may be formulated in a wide range of delivery systems each tailored for specific healthcare applications

 
 
 

Potent anti-biofilm effect

SALTech (a derivative of ViruSAL) has been tailored to provide potent inhibition and reduction of established microbial

biofilm. SALTech is significantly more effective than conventional agents such as chlorhexidine or povidone iodine

 
 

Anti-Biofilm Application in Surgical Irrigation

Inhibition of Microbial Adhesion and Ablation of Existing Biofilm provides significant utility in Surgical Irrigation.

In this example, sections of excised human colon were flushed with SALTech. Significantly greater reduction of bioburden was achieved compared to the conventional povidone Iodine wash