Publications

Selected ViruSAL relevant Publications from Academic Collaborators*

*Westgate Biomedical’s industry sponsored work is commercially sensitive and not presented for scientific publication.

 
 
 

Folan. M. Antimicrobial Compositions Containing Fatty Acids 2011 Patent publication WO 2011/061237 A1

The invention concerns antimicrobial compositions comprising free fatty acids emulsified with membrane lipids or hydrolysed derivatives thereof, and pharmaceutical formulations comprising same. Patent Granted: USA, Canada, EU (16 states), China.

 

 

Fletcher et.al. 

A Novel Antiviral Formulation Inhibits a Range of Enveloped Viruses

J. General Virology 2020; 101: pp 1090-1102

Excerpt of Abstract: Some free fatty acids derived from milk and vegetable oils are known to have potent antiviral and antibacterial properties. However, therapeutic applications of short- to medium-chain fatty acids are limited by physical characteristics such as immiscibility in aqueous solutions. We evaluated a novel proprietary formulation based on an emulsion of short-chain caprylic acid, ViroSAL, for its ability to inhibit a range of viral infections

 

 

Hogan et.al  

Eradication of Staph aureus catheter-related Biofilm using ML:8 and Citrox

Antimicrobial Agents and Chemotherapy. 2016, Vol 60 No 10: 5968-5975

Excerpt of Abstract: Staphylococci are a leading cause of catheter-related infections (CRIs) due to biofilm formation. CRIs are typically managed by either device removal or systemic antibiotics, often in combination with catheter lock solutions (CLSs). CLSs provide high concentrations of the antimicrobial agent at the site of infection. However, the most effective CLSs against staphylococcal biofilm-associated infections have yet to be determined. The purpose of this study was to evaluate the efficacy and suitability of two newly described antimicrobial agents, ML:8 and Citrox, as CLSs against Staphylococcus aureusbiofilms

 

 

McDermott et. al

Gnotobiotic Human Colon Ex Vivo.

Gastroenterology Research. 2015 (5):247-252

A novel emulsion with efficacy as an agent for elimi-nating biofilms was selected. The aim of this study was to examine efficacy and effect of a formulation of ML:8 against commensal bacteria harvested from ex vivo human colonic tissues.

 

 

Laverty et. al              

Antimicrobial Efficacy of a novel emulsion of triglycerides against canine and feline periodontal pathogens

J. Small Animal practice 56 (4). 253 – April 2015

To test the in vitro antimicrobial efficacy of a non-toxic emulsion of free fatty acids against clinically relevant canine and feline periodontopathogens.